Relationship between beta-adrenergic binding in lymphocyte and severity of disease in asthma.
نویسندگان
چکیده
A proposed theory for the development of bmmhial asthma suggests the presence of partial or complete blockage of the beta-adrenergic nervous sy~ tem. l~~ Evidence to support this hypothesis stems from observations that individuals with bronchial astbma have increased sensitivity to beta-adrenergic blocking agents, as well as specific pharmacologic, physiologic and biochemical alteration~.~-~ The present investigation was designed to assess lymphocyte beta-adrenergic receptors in asthma employing binding studies using labeled dihydroalprenolol (DHA).a-11 In addition, the effects of hydrocortisone on DHA binding was also investigated.
منابع مشابه
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عنوان ژورنال:
- Chest
دوره 75 2 Suppl شماره
صفحات -
تاریخ انتشار 1979